Most opt to change out the K-frame (to the correct big block one) because its heavier duty than the slant-6 K-frame.
The 440 motor (for example) weighs about 40% more (not counting the tranny) than the slant-6. Furthermore, the slant-6 torsion bars just can't hold up the same car with a 440 motor. It will bottom out turning into driveways, and could even punch a hole in the oil pan. Hitting a pothole at highway speed could cause an accident.
For this reason, there has been little demand for "conversion brackets" from a slant-6 to a big block using the slant-6 K-frame. But, there's nothing stopping you from giving it a try. In my experience, when converting from the slant-6 to a big block, torsion bars and K-frame seem the minimum one must change to get the car drivable.
Another key point with using the "correct" K-frame, is there are fewer surprises. Things will just bolt right into place. Working a combination few have completed in the past, tends to create more issues than it solves. For me, I find the frustration of not knowing how to resolve an issue, or the need to tow the car in to a shop to have something conjured and fabricated, just isn't worth it, compared to how nicely things come together doing things the way "the factory did them."
If you're not sure you got the budget to make the conversion, don't feel bad. Many of us are in the same boat. Original parts are becoming more and more scarce. Some of us have to wait years before we can find the right parts at the right price. Some engine combinations (an original 426 Hemi car, for example) are out of my league, budget-wise.
If you want a cool-ish collector car when you're done, a car you can enjoy, and may be able to resell some day and recover the costs, it's not a horrible idea to try and find a replacement slant-6 motor. While this may not afford the prestige some of the other motors offer, it would likely cost you a great deal less to go this route.
You won't find a shortage of opinions asking for advice around here. It's still your call, and we can all respect whatever choice you make.